Uklanjanje farmaceutika RO/NF membranama iz voda u kiselim uvjetima

master's thesis

• Title (english): Removal of pharmaceuticals with RO/NF membranes from water in acidic conditions
• Author: Kristina Vertuš
• Mentor: Davor Dolar (mentor)
• Committee member: Davor Dolar (predsjednik povjerenstva)
• Committee member: Krešimir Košutić (član povjerenstva)
• Committee member: Danijela Ašperger (član povjerenstva)
• Granter: University of Zagreb; Faculty of Chemical Engineering and Technology; Zagreb
• Defense date and country: 2015-09-25, Croatia
• Scientific / art field, discipline and subdiscipline: TECHNICAL SCIENCES; Chemical Engineering; Mechanical, Thermal and Separation Processes

Abstract

Prisutnost lijekova u okolišu svakodnevno raste zbog sve veće primjene u zdravstvu i veterini. Ovaj rad ispitivao je učinkovitost i mehanizam uklanjanja odabranih veterinarskih farmaceutika (sulfagvanidin, trimetoprim, hidrokortizon, prokain · HCl i albendazol) iz voda u kiselim uvjetima RO/NF membranama (XLE, NF, NF270). Učinkovitost uklanjanja farmaceutika iz voda u kiselim uvjetima ovisilo je o veličini pora membrane i veličini farmaceutika, o interakcijama između farmaceutika i membrane, te fizikalno-kemijskim karakteristikama farmaceutika. Pokazano je da je mehanizam isključenja prema veličini dominantan mehanizam. Rezultatima FTIR analize utvrđeno je postojanje interakcija između membrane i farmaceutika, čak i hidrofilnih farmaceutika i membranama, posebno kod membrana većih pora i većeg protoka.

Abstract (english)

The presence of drugs in the environment is increasing daily due to the increasing applications in medicine and veterinary. This paper examines the retention and removal mechanism of selected veterinary pharmaceuticals (sulfaguanidine, trimethoprim, hydrocortisone, procaine · HCl and albendazole) from water in the acidic conditions of RO/NF membrane (XLE, NF, NF270). The effectiveness of removing pharmaceuticals from water in acidic conditions depended on the size of membrane pores and the size of pharmaceuticals, the interaction between pharmaceuticals and membranes, and physico-chemical characteristics of pharmaceuticals. Dominant rejection mechanism of the examined pharmaceuticals was the size exclusion. Results of FTIR analysis point to the existence of interaction between the membrane and pharmaceuticals, even hydrophilic pharmaceuticals and membranes, especially with the membrane with bigger pores and higher flux.

• Keywords: reverzna osmoza; nanofiltracija; farmaceutici; uklanjanje
• Keywords (english): reverse osmosis; nanofiltration; pharmaceutical; retention
• Language: croatian
• URN:NBN: urn:nbn:hr:149:948118
• Study programme: Title: Environmental Engineering - Graduate study; Study programme type: university; Study level: graduate; Academic / professional title: magistar/magistra inženjer/inženjerka ekoinženjerstva (magistar/magistra inženjer/inženjerka ekoinženjerstva)
• Type of resource: Text
• File origin: Born digital
• Access conditions: Open access
• Created on: 2017-03-14 10:09:52