Poboljšanje učinkovitosti u procesu izluživanja fenolnih spojeva iz lista masline

master's thesis

• Title (english): Efficiency improvement in leaching of phenolic compounds from olive leaf
• Author: Nataša Marolt
• Mentor: Jasna Prlić Kardum (mentor)
• Committee member: Jasna Prlić Kardum (predsjednik povjerenstva)
• Committee member: Aleksandra Sander (član povjerenstva)
• Committee member: Dajana Kučić Grgić (član povjerenstva)
• Granter: University of Zagreb; Faculty of Chemical Engineering and Technology; Zagreb
• Defense date and country: 2018-07-12, Croatia
• Scientific / art field, discipline and subdiscipline: TECHNICAL SCIENCES; Chemical Engineering; Mechanical, Thermal and Separation Processes

Abstract

Lišće masline, najčešće prisutne biljke u Mediteranskim zemljama, predstavlja vrlo važan izvor biološki aktivnih tvari koje imaju pozitivan učinak na ljudsko zdravlje. Najvažniji za istaknuti su snažni antioksidansi - fenolni spojevi, koji imaju sposobnost vezanja slobodnih radikala. Branjem i obradom maslina, velika količina lišća zaostaje kao otpad. Obradom lišća zaostalog u obliku otpada, mogu se izdvojiti vrijedne nutritivne komponente koje se dalje mogu upotrijebiti u farmaceutskoj industriji. Zahvaljujući visokom sadržaju fenolnih spojeva te brojnim pozitivnim učincima na ljudsko zdravlje, lišće masline postalo je tema brojnih istraživanja. Sukladno načelima zelene kemije, traže se potencijalna rješenja za poboljšanje učinkovitosti procesa ekstrakcije biološki aktivnih komponenti iz biljnog materijala. Nova, dizajnirana prirodna eutektička otapala, kao nehlapljiva, netoksična i obnovljiva otapala koja zadovoljavaju načela zelene kemije, pokazala su veću učinkovitost u procesu izluživanja biološki aktivnih komponenti iz biljnog materijala od konvencionalnih otapala ili vode. Nadalje, u novije vrijeme se ispituje mogućnost poboljšanja prijenosa tvari tijekom ekstrakcije uz pomoć stabilnih nanosuspenzija pripremljenih raspršenjem nanočestica u odgovarajućem prirodnom eutektičkom otapalu. U ovom radu ispitana je mogućnost poboljšanja učinkovitosti izluživanja fenolnih spojeva iz lišća masline pomoću prirodnog eutektičkog otapala i pomoću njemu pripadajuće, stabilne nanosuspenzije. Određeno je optimalno vrijeme trajanja ekstrakcije i definiran učinkovit način miješanja. Također, ispitan je utjecaj temperature i veličine čestica na učinkovitost procesa.

Abstract (english)

Olive leaves, part of the most common plant in the Mediterranean countries, represents a very important source of biologically active substances that have a positive effect on human health. The most important substances are the strong antioxidants – phenolic compounds, which have the ability to bind free radicals. However, with the harvesting and processing of olive fruits, a large amount of leaves is lagging behind as a waste. By processing residual leaves in the form of waste, valuable nutritional components can be extracted and used in the pharmaceutical industry. Thanks to the high content of phenolic compounds and many positive effects on human health, olive leaves have become the subject of numerous researches. In accordance with the principles of green chemistry, potential solutions are being sought to improve the efficiency of the extraction process of biologically active components from plant material. New, designed natural deep eutectic solvents, non-volatile, non-toxic and renewable solvents that meet the principles of green chemistry, have shown greater efficacy in the process of leaching biologically active components from plant material than conventional solvents or water. Furthermore, in recent years, the possibilities of improving the mass transfer during extraction process is investigated with the help of the stable nanosuspension, prepared by dispersing nanoparticles in a suitable natural deep eutectic solvent. In this study, the possibility of improving the efficiency of the phenolic compounds extraction from olive leaves using natural deep eutectic solvent and its corresponding stable nanosuspension was investigated. Optimum duration of extraction was determined and effective mixing method was defined. Also, the influence of temperature and particle size on the efficiency of the process was studied.

• Keywords: list masline; fenolni spojevi; ekstrakcija; prirodno eutektičko otapalo; nanosuspenzija
• Keywords (english): olive leaves; phenolic compounds; extraction; natural deep eutectic solvent; nanosuspension
• Language: croatian
• URN:NBN: urn:nbn:hr:149:205104
• Study programme: Title: Chemical Engineering - Graduate study; Study programme type: university; Study level: graduate; Academic / professional title: magistar/magistra inženjer/inženjerka kemijskog inženjerstva (magistar/magistra inženjer/inženjerka kemijskog inženjerstva)
• Type of resource: Text
• File origin: Born digital
• Access conditions: Open access
• Created on: 2020-06-02 12:01:45