Pripema i karakterizacija mješavina na osnovi fibroina svile i poliuretana

master's thesis

• Title (english): Preparation and characterization of silk fibroin/polyurethane blends
• Author: Luka Benić
• Mentor: Emi Govorčin Bajsić (mentor)
• Committee member: Emi Govorčin Bajsić (predsjednik povjerenstva)
• Committee member: Ljerka Kratofil Krehula (član povjerenstva)
• Committee member: Igor Sutlović (član povjerenstva)
• Granter: University of Zagreb; Faculty of Chemical Engineering and Technology; Zagreb
• Defense date and country: 2019-07-11, Croatia
• Scientific / art field, discipline and subdiscipline: TECHNICAL SCIENCES; Chemical Engineering

Abstract

Termoplastični poliuretan (TPU) je vrlo poželjan materijal za medicinsku primjenu zbog njegove fleksibilnosti, trajnosti i otpornosti na ulja i kemikalije. S druge strane, fibroin svile je jedinstveni i obećavajući prirodni materijal dobiven iz dudovog svilca te zbog svoje biokompatibilnosti, biorazgradivosti i netoksičnosti ima veliki potencijal za primjenu kao biomedicinski materijal. Cilj ovoga rada bio je pripremiti i karakterizirati fizikalna, toplinska i mehanička svojstva mješavina sastavljenih od elastičnog termoplastičnog poliuretana (TPU) u koji je umješan različiti udio fibroina svile (FS). TPU/FS mješavine pripremljene su dodatkom 5%, 10%, 15% i 20 mas% FS umješavanjem u laboratorijskoj Brabender gnjetilici. Uzorci čistih komponenti i mješavina dobiveni su prešanjem na hidrauličkoj preši. Određena je struktura, toplinska i mehanička svojstva čistih komponenata (TPU i FS) i njihovih mješavina (TPU/FS) primjenom infracrvene spektroskopije s Fourierovim transformacijama (FT-IR) i prigušene totalne refleksije (ATR), diferencijalnom pretražnom kalorimetrijom (DSC) i termogravimetrijskom analizom (TGA). Mehanička svojstva čistih komponenata i mješavina određena su testom rasteznog naprezanja upotrebom mehaničke kidalice. Dobiveni rezultati FTIR analize pokazuju da je fibroin svile ugrađen u TPU matricu. Rezultati dobiveni DSC tehnikom pokazali su da se dodatkom fibroina svile temperatura staklastog prijelaza povećava, dok se talište smanjuje, zbog nastajanja slabije uređene kristalne strukture nastale dodatkom fibroina svile. Toplinska stabilnost određena je termogravimetrijskom analizom iz koje se vidi da se dodatkom fibroina svile smanjuje toplinska stabilnost TPU/FS mješavina. Povećanjem udjela fibroina svile prekidna čvrstoća i prekidno istezanje se smanjuju.

Abstract (english)

Thermoplastic polyurethane (TPU) is very desirable for medical applications because of its flexibility , durability, and resistance against oils and chemicals. Silk fibroin (SF), a unique and promising natural material extracted from silkworm, has gained much attention for its use as biomedical material, because of its biocompatibility, biodegradability and nontoxicity. The aim of this work was to preparation and characterization the mechanical, physical and thermal properties of blends containing a highly elastic thermoplastic polyurethane (TPU) compounded with different silk contents. TPU/SF blends were prepared with melt mixing of TPU with 5%, 10%, 15% i 20 wt% of SF in a laboratory Brabender mixer. The specimenes of the neat components and their blends were molded in hydraulic press. The structural characteristics, thermal and mechanical properties of the neat TPU, SF and their blends (TPU/SF) were examined by Fourier transform infrared (FT-IR) spectroscopy, differential scanning calorimetry (DSC) and thermogravimetric analysis (TGA). Mechanical properties of the neat components and their blends were determined by a tensile test using universal testing machine. The FTIR results showed that the silk fibroin was successfully introduced to TPU scaffolds. Results obtained with DSC showed that with addition of silk fibroin, glass transition temperature increases, while melting temperature and degree of crystallinity decreases, because of the less organized crystal structure with addition of silk fibroin. Thermal stability is determined by TGA which shows that with addition of silk fibroin thermal stability decreased. With increasing SF content, the tensile strength and elongation at break decreased.

• Keywords: mješavine; termoplastični poliuretan; fibroin svile; toplinska svojstva; mehanička svojstva; diferencijalna pretražna kalorimetrija; termogravimetrijska analiza; infracrvena spektroskopija
• Keywords (english): blends; thermoplastic polyurethane; silk fibroin; thermal properties; mechanical properties; differential scanning calorimetry; thermogravimetric analysis; infrared spectroscopy
• Language: croatian
• URN:NBN: urn:nbn:hr:149:553178
• Study programme: Title: Materials Science and Engineering - Graduate study; Study programme type: university; Study level: graduate; Academic / professional title: magistar/magistra inženjer/inženjerka kemijskog inženjerstva (magistar/magistra inženjer/inženjerka kemijskog inženjerstva)
• Type of resource: Text
• File origin: Born digital
• Access conditions: Open access
• Created on: 2022-02-16 12:45:50