Polimerni sustavi za dostavu lijeka

undergraduate thesis

• Title (english): Polymer systems for drug delivery
• Author: Martina Omazić
• Mentor: Marica Ivanković (mentor)
• Committee member: Marica Ivanković (predsjednik povjerenstva)
• Committee member: Antonia Ressler (član povjerenstva)
• Committee member: Hrvoje Ivanković (član povjerenstva)
• Granter: University of Zagreb; Faculty of Chemical Engineering and Technology; Zagreb
• Defense date and country: 2021-09-16, Croatia
• Scientific / art field, discipline and subdiscipline: NATURAL SCIENCES; Chemistry

Abstract

Ovaj rad predstavlja literaturni pregled različitih polimernih sustava koji se upotrebljavaju za dostavu lijekova te je opisan njihov mehanizam djelovanja. Netoksični, biorazgradljivi i biokompatibilni polimeri imaju izuzetnu važnost u dostavi lijekova. Osnovna uloga polimera je zaštititi lijek od fiziološke okoline tijekom prijenosa do ciljanog mjesta i poboljšati njegovu stabilnost prilikom oslobađanja. Dostava lijeka na točno određeno mjesto omogućava prepoznavanje i reagiranje na fiziološke promjene u ljudskom organizmu. Biorazgradljivi polimeri nalaze široku primjenu u isporuci lijekova jer se mogu razgraditi na netoksične monomere u tijelu. Sinteza novih kombinacija polimera u budućnosti proširit će opseg novih sustava za dostavu lijekova.

Abstract (english)

This work presents a literature review of the different polymeric systems used for the delivery of medicinal products and describes their mechanism of action. Non-toxic, biodegradable and biocompatibile polymers have great importance in the delivery of drugs. The main role of the polymer is to protect the drug form the physiological environment during transmission to the target site and improve its stability when releasing. Delivery of the drug to a specific place enables the recognition and reacting to physiological changes in the human body. Biodegradable polymers are widely used in the delivery of drugs because they can be decomposed into non-toxic monomers in the body. The synthesis of new polymer combinations in the future will expand the scope of new drug delivery systems.

• Keywords: polimeri; dostava lijeka; biorazgradljivi polimeri
• Keywords (english): polymers; drug delivery; biodegradable polymers
• Language: croatian
• URN:NBN: urn:nbn:hr:149:171097
• Study programme: Title: Applied Chemistry - Undergraduate study; specializations in: Environmental chemistry and green technologies, Advanced materials and technologies, Applied organic chemistry; Course: Applied organic chemistry; Study programme type: university; Study level: undergraduate; Academic / professional title: sveučilišni/a prvostupnik/prvostupnica (baccalaureus/baccalaurea) primijenjene kemije (sveučilišni/a prvostupnik/prvostupnica (baccalaureus/baccalaurea) primijenjene kemije)
• Type of resource: Text
• File origin: Born digital
• Access conditions: Access restricted to students and staff of home institution
• Created on: 2023-04-12 11:13:42