Svojstva i primjene pH osjetljivih polimera

undergraduate thesis

• Title (english): Properties and applications of pH-responsive polymers
• Author: Ivana Komparić
• Mentor: Marica Ivanković (mentor)
• Committee member: Marica Ivanković (predsjednik povjerenstva)
• Committee member: Nevenka Vrbos (član povjerenstva)
• Committee member: Hrvoje Ivanković (član povjerenstva)
• Granter: University of Zagreb; Faculty of Chemical Engineering and Technology; Zagreb
• Defense date and country: 2020-09-14, Croatia
• Scientific / art field, discipline and subdiscipline: TECHNICAL SCIENCES; Chemical Engineering

Abstract

Cilj je ovog rada dati literaturni prikaz istraživanja svojstava pH osjetljivih polimera i njihove primjene u dostavi lijekova. Nova saznanja u području inženjerstva materijala omogućila su napredak u ciljanim liječenjima malignih bolesti. Svojstva pH osjetljivih polimera, poput biokompatibilnosti i biorazgradljivosti, danas su ključna za primjenu u medicini. Promjene strukture kojima podliježu ovi polimeri s obzirom na uvjete u okolini u kojoj se nalaze omogućuju efektivniju dostavu lijekova, vremensko otpuštanje djelatne tvari te smanjenje nuspojava. Prikazani su najčešći načini sinteze pH osjetljivih polimera, njihove najčešće strukture i strukturalne promjene kojima podliježu pri promjeni pH.

Abstract (english)

Aim of this work is to give a literature review of the research of pH-responsive polymers and their applications in drug delivery. New findings in the field of material science have improved targeted treatments of malignant diseases. Properties of pH-responsive polymers, such as biocompatibility and biodegradation, are key for medical applications. Changes in structure of these polymers occur when there are changes in their environment. That provides more effective drug delivery, time release of active substance and reduction of side effects. Most commonly used methods for synthesis of the pH-responsive polymers are shown, their most common structures and structure changes they undergo when the environmental pH changes.

• Keywords: pH osjetljivi polimeri; pametni materijali; kontrolirana radikalska polimerizacija; dostava lijekova
• Keywords (english): pH-responsive polymers; inteligent materials; controlled radical polymerization; drug delivery
• Language: croatian
• URN:NBN: urn:nbn:hr:149:618761
• Study programme: Title: Materials Science and Engineering - Undergraduate study; Study programme type: university; Study level: undergraduate; Academic / professional title: sveučilišni/a prvostupnik/ prvostupnica (baccalaureus/baccalaurea) inženjer/inženjerka kemijskog inženjerstva (sveučilišni/a prvostupnik/ prvostupnica (baccalaureus/baccalaurea) inženjer/inženjerka kemijskog inženjerstva)
• Type of resource: Text
• File origin: Born digital
• Access conditions: Access restricted to students and staff of home institution
• Created on: 2023-05-04 11:29:44