Analiza čepova u farmaceutskoj industriji

master's thesis

• Title (english): Analysis of stoppers in pharma industry
• Author: Željka Kašaj
• Mentor: Juraj Šipušić (mentor)
• Committee member: Juraj Šipušić (predsjednik povjerenstva)
• Committee member: Sandra Babić (član povjerenstva)
• Committee member: Mirjana Novak Stankov (član povjerenstva)
• Granter: University of Zagreb; Faculty of Chemical Engineering and Technology; Zagreb
• Defense date and country: 2018-09-28, Croatia
• Scientific / art field, discipline and subdiscipline: TECHNICAL SCIENCES; Chemical Engineering; Analysis, Synthesis and Management of Chemical Processes

Abstract

Farmaceutski proizvodi koji se primjenjuju parenteralno su dizajnirani, formulirani i pakirani tako da budu sterilni i da zadržavaju svoju sterilnost. Čepovi i odgovarajući spremnik čine primarnu ambalažu takvih proizvoda. Cilj ovog rada je upoznati se s pojmom gumenih čepova u sterilnoj proizvodnji, njihovim sastavom, čišćenjem, sterilizacijom, silikonizacijom, premazivanjem i njihovom interakcijom s farmaceutskim proizvodom. Eksperimentalni dio rada opisuje analize kojima se gumeni čepovi trebaju podvrgnuti u farmaceutskoj industriji prije formiranja gotovog proizvoda.

Abstract (english)

Pharmaceutical products that are administered parentally are designed, formulated and packaged so that they are sterile and retain their sterility. Bottles and an appropriate stoppers make the primary packaging of such products. The aim of this work is to introduce the term "rubber stoppers" in sterile production, their composition, purification, sterilization, siliconization, coating and their interaction with a pharmaceutical product. The experimental part of the work describes the analysis by which the rubber stoppers should be subjected to the pharmaceutical industry prior to the formation of the finished product.

• Keywords: farmacija; čepovi; gumeni čepovi; sterilizacija
• Keywords (english): farmacy; stoppers; rubber stoppers; sterilization
• Language: croatian
• URN:NBN: urn:nbn:hr:149:965059
• Study programme: Title: Chemical Engineering - Graduate study; Study programme type: university; Study level: graduate; Academic / professional title: magistar/magistra inženjer/inženjerka kemijskog inženjerstva (magistar/magistra inženjer/inženjerka kemijskog inženjerstva)
• Type of resource: Text
• File origin: Born digital
• Access conditions: Open access
• Created on: 2020-11-02 13:00:14