Sinteza i spektroskopska karakterizacija Schiffove baze benzimidazola kao potencijalnog senzora za metalne katione i pH u otopinama

undergraduate thesis

• Title (english): Synthesis and spectroscopic characterization of benzimidazole Schiff base as potential sensor for metal cations and pH in solution
• Author: Marija Ćurić
• Mentor: Marijana Hranjec (mentor)
• Committee member: Marijana Hranjec (predsjednik povjerenstva)
• Committee member: Maja Cindrić (član povjerenstva)
• Committee member: Jasna Prlić Kardum (član povjerenstva)
• Granter: University of Zagreb; Faculty of Chemical Engineering and Technology; Zagreb
• Defense date and country: 2018-09-07, Croatia
• Scientific / art field, discipline and subdiscipline: NATURAL SCIENCES; Chemistry; Organic Chemistry

Abstract

U okviru ovog rada provedena je sinteza Schiffovih baza benzimidazola kao potencijalnih senzora za pH i metalne katione u otopinama. Za pripravu ciljanih molekula korištene su klasične reakcije organske sinteze te mikrovalovima potpomognuta sinteza. Ciljani produkti 8-10 priređeni su reakcijom kondenzacije odgovarajućih aldehida 5-7 i 2-amino-5-cijano-N-metilbenzimidazola 4. Ciljani spojevi 9 i 10 su izolirani, dok je spoj 8 sintetiziran međutim nije uspješno izoliran. Strukture priređenih spojeva su potvrđene 1H i 13C NMR spektroskopijom te su dodatno okarakterizirani UV/Vid spektroskopijom. Kako bi se potvrdila mogućnost primjene ovih spojeva kao senzora za pH ili za određivanje metalnih kationa u otopinama provedene su UV/Vid titracije otopina spojeva s puferima različitog pH ili s otopinama metalnih soli.

Abstract (english)

The aim of this study was the synthesis of benzimidazole Schiff bases as potential sensors for pH and metal cations in solution. For the preparation of targeted molecules, classical reactions of organic synthesis and microwave-assisted synthesis were used. The target compounds 8-10 were prepared in the condensation of appropriate benzaldehydes 5-7 and 2-amino-5-cyano-N-methylbenzimidazole 4. The targeted compounds 9 and 10 were isolated while compound 8 was synthesized but was not successfully isolated. The structures of all synthesized compounds were confirmed by 1H and 13C NMR spectroscopy and were additionally characterized by UV/Vis spectroscopy. To explore the possibility of synthesized compounds for their application as sensors for pH or metal cations in solution, UV/Vis titrations of aqueous compounds solutions with aqueous solutions of metal chloride salts or with buffers having different pH were performed.

• Keywords: benzimidazoli; Schiffove baze; organska sinteza; 1H i 13C NMR; UV/Vid spektroskopija; senzori; pH
• Keywords (english): benzimidazoles; Schiff bases; organic synthesis; 1H and 13C NMR; UV/Vis spectroscopy; sensors; pH
• Language: croatian
• URN:NBN: urn:nbn:hr:149:814379
• Study programme: Title: Chemical Engineering - Undergraduate study; Study programme type: university; Study level: undergraduate; Academic / professional title: sveučilišni/a prvostupnik/ prvostupnica (baccalaureus/baccalaurea) inženjer/inženjerka kemijskog inženjerstva (sveučilišni/a prvostupnik/ prvostupnica (baccalaureus/baccalaurea) inženjer/inženjerka kemijskog inženjerstva)
• Type of resource: Text
• File origin: Born digital
• Access conditions: Open access
• Created on: 2021-06-24 11:54:48