Priprava N,N-disupstituiranih derivata dimetoksianilina

undergraduate thesis

• Title (english): Preparation of the N,N-disubstituted derivatives of dimethoxyaniline
• Author: Marina Monika Marić
• Mentor: Dragana Vuk (mentor)
• Committee member: Dragana Vuk (predsjednik povjerenstva)
• Committee member: Irena Škorić (član povjerenstva)
• Committee member: Vilko Mandić (član povjerenstva)
• Granter: University of Zagreb; Faculty of Chemical Engineering and Technology; Zagreb
• Defense date and country: 2020-09-25, Croatia
• Scientific / art field, discipline and subdiscipline: NATURAL SCIENCES; Chemistry

Abstract

U sklopu izrade ovog završnog rada proveden je niz pokušaja reakcije aminacije. Izučavane su reakcije sinteze potpomognute mikrovalovima, reakcije aminacije bez prisustva metalnih katalizatora, reakcije uz prisustvo n-BuLi, te reakcije alkiliranja. Kao najpogodnija metoda pokazala se reakcija uz n-BuLi pomoću koje su dobivena tri produkta u dobrom iskorištenju, N,N-diizobutil-3,5-dimetoksianilin (2), N,N-difenil-3,5-dimetoksianilin (3), te
1-(3,5-dimetoksifenil)piperidin (4). Osim spomenute metode, kao uspješna reakcija pokazala se i reakcija alkiliranja, odnosno metiliranja, čijom je primjenom dobiven
N,N-dimetil-3,5-dimetoksianilin (6) u iskorištenju od 100%.

Abstract (english)

The aim of this work was to conduct a number of amination reaction attempts. A series of reactions have been studied, such as reactions using microwave irradiation, amination reactions without transition-metal catalyst, reactions using n-BuLi, and alkylation reactions. The most convenient method was the reaction using n-BuLi. The utilization of that method resulted in synthesis of three products in good yields, N,N-diisobutyl-3,5-dimethoxyaniline (2), N,N-diphenyl-3,5-dimethoxyaniline (3), te 1-(3,5-dimethoxyphenyl)piperidine (4). Besides the reaction with n-BuLi, methylation is another method that successfully produced a desired product, N,N-dimethyl-3,5-dimethoxyaniline (6) in 100% yield.

• Keywords: arilamini; reakcije aminacije; mikrovalna sinteza; n-butil-litij; metiliranje
• Keywords (english): arylamines; amination reactions; microwave irradiation synthesis; n-butyl-lithium; methylation
• Language: croatian
• URN:NBN: urn:nbn:hr:149:245124
• Project: Number: PZS-2019-02-1555; Title: Fotonaponska-geopolimerna fasada: uloga vode-kisika u naprednom sklapanju filmova kompozitnih materijala; Title: Photovoltaic-geopolymer facade: the water-oxygen role in the advanced assembly of layered composite materials; Acronym: PV-WALL; Leader: Vilko Mandić; Jurisdiction: Croatia; Funder: HRZZ; Funding stream: PZS
• Project: Number: UIP-2019-04-2367; Title: Fenomeni na površini tijekom priprave naprednih nanokompozita infiltracijom i funkcionalizacijom poroznih materijala; Title: Surface limitations in preparing and infiltration of hard porous nanomaterial by soft or liquid precursors for performance enhancing; Acronym: SLIPPERYSLOPE; Leader: Vilko Mandić; Jurisdiction: Croatia; Funder: HRZZ; Funding stream: UIP
• Study programme: Title: Materials Science and Engineering - Undergraduate study; Study programme type: university; Study level: undergraduate; Academic / professional title: sveučilišni/a prvostupnik/ prvostupnica (baccalaureus/baccalaurea) inženjer/inženjerka kemijskog inženjerstva (sveučilišni/a prvostupnik/ prvostupnica (baccalaureus/baccalaurea) inženjer/inženjerka kemijskog inženjerstva)
• Type of resource: Text
• File origin: Born digital
• Access conditions: Closed access
• Created on: 2023-05-05 10:32:56