Mehanokemijska sinteza cerijeva fosfata

master's thesis

• Title (english): Mechanochemical synthesis of cerium phosphate
• Author: Vanesa Mihajlović
• Mentor: Stanislav Kurajica (mentor)
• Committee member: Stanislav Kurajica (predsjednik povjerenstva)
• Committee member: Krunoslav Žižek (član povjerenstva)
• Committee member: Katarina Mužina (član povjerenstva)
• Granter: University of Zagreb; Faculty of Chemical Engineering and Technology; Zagreb
• Defense date and country: 2023-10-27, Croatia
• Scientific / art field, discipline and subdiscipline: TECHNICAL SCIENCES; Chemical Engineering

Abstract

Ovaj rad bavi se mehanokemijskom sintezom nanočestica, novog potencijalnog UV filtra, cerijeva (III) fosfata. Radi se o obećavajućem materijalu za primjenu u formulacijama za zaštitu od Sunca, zbog dobrih svojstava aspsorpcije UV dijela spektra, niskog indeksa loma, relativne prozirnosti za vidljivo svjetlo te kemijske inertnosti. U tu svrhu, nanočestice CePO4 sintetizirane su u planetarnom mlinu iz različitih prekursora (natrijeva fosfata dodekahidrata, natrijeva dihidrogenfosfat hidrata, natrijeva hidrogenfosfata) uz cerijev klorid kao drugi reaktant i natrijev klorid kao razrjeđivač, uz različito vrijeme miješanja (15, 30 i 60 minuta), kako bi se utvrdili optimalni uvjeti. Kao najpogodnija, ispostavila se sinteza u posudi od cirkonijeva dioksida, iz natrijeva fosfata dodekahidrata u trajanju od 15 minuta, pri čemu se dobivaju nanočestice rabdofana (CePO4 ∙ H2O). Dobiveni prašci karakterizirani su rendgenskom difrakcijskom analizom (XRD), diferencijalnom termalnom i termogravimetrijskom analizom (DTA/TGA), infracrvenom spektroskopijom s Fourierovom transformacijom (FTIR), pretražnom elektronskom mikroskopijom (SEM) i difuznom refleksijskom spektroskopijom (DRS). Uz to određena je raspodjela veličina čestica uzorka u vodi i ulju, adsorpcijsko-desorpcijske izoterme, fotokatalitička aktivnost u procesu fotokatalize ricinusovog ulja te citotoksičnost u usporedbi s trenutno najčešće korištenim anorganskim
UV filtrom, titanijevim dioksidom. Niska fotokatalitička aktivnost, visoka apsorpcija u
UV području kao i niska citotoksičnost ukazali su na moguću primjenu rabdofana kao UV filtra u novim formulacijama fotoprotektivnih sredstava kako bi se zamijenili trenutno korišteni anorganski UV filtri ZnO i TiO2.

Abstract (english)

This thesis provides the insight into mechanochemical synthesis of nanoparticles of a new and potential UV filter, cerium (III) phosphate. It is a promising material for use in sunscreen formulations due to its good absorption properties of the UV part of the spectrum, low refractive index, relative transparency to visible light and chemical inertness.
For this purpose, CePO4 nanoparticles were synthesized in a planetary mill from different precursors (sodium phosphate dodecahydrate, sodium dihydrogenphosphate hydrate, sodium hydrogenphosphate) with cerium chloride as a second reactant and sodium chloride as a diluent, with different mixing times (15, 30 and 60 minutes), in order to determine the optimal conditions. Synthesis in a zirconium dioxide vessel with sodium phosphate dodecahydrate for 15 minutes turned out to be the most suitable, whereby nanoparticles of rhabdophan (CePO4 ∙ H2O) are obtained. The resulting powders were characterized by X-ray diffraction analysis (XRD), differential thermal and thermogravimetric analysis (DTA/TGA), Fourier transform infrared spectroscopy (FTIR), scanning electron microscopy (SEM), diffuse reflection spectroscopy (DRS). In addition, the size distribution of the particle sample in water and oil, the adsorption-desorption isotherm, the photocatalytic activity in the photocatalysis process of castor oil, and the cytotoxicity in relation to the currently most commonly used filter, titanium dioxide, were determined. Low photocatalytic activity, high absorption of the UV range as well as low cytotoxicity indicated the possible use of rhabdophane as a UV filter in new formulations of photoprotective agents to replace the currently used inorganic UV filters ZnO and TiO2.

• Keywords: cerijev(III) fosfat; mehanokemijska sinteza; UV filtar; citotoksičnost; fotoprotektivna primjena
• Keywords (english): cerium (III) phosphate; mechanochemical synthesis; UV filter; cytotoxicity; photoprotective application
• Language: croatian
• URN:NBN: urn:nbn:hr:149:978303
• Study programme: Title: Applied Chemistry - Graduate study; specializations in: Environmental chemistry and green technologies, Advanced materials and technologies, Applied organic chemistry; Course: Applied organic chemistry; Study programme type: university; Study level: graduate; Academic / professional title: sveučilišni/a magistar/magistra primijenjene kemije (sveučilišni/a magistar/magistra primijenjene kemije)
• Type of resource: Text
• File origin: Born digital
• Access conditions: Embargoed access; Embargo expiration date: 2025-10-27
• Created on: 2023-11-24 15:31:46