Prisutnost COVID-19 lijekova u okolišu

undergraduate thesis

• Title (english): Presence of COVID-19 drugs in the environment
• Author: Lucija Vrbić
• Mentor: Dajana Kučić Grgić (mentor)
• Committee member: Dajana Kučić Grgić (predsjednik povjerenstva)
• Committee member: Lidija Furač (član povjerenstva)
• Committee member: Vesna Ocelić Bulatović (član povjerenstva)
• Granter: University of Zagreb; Faculty of Chemical Engineering and Technology; Zagreb
• Defense date and country: 2023-09-21, Croatia
• Scientific / art field, discipline and subdiscipline: TECHNICAL SCIENCES; Chemical Engineering

Abstract

Nakon pojave virusa COVID-19 zbog visoke zaraznosti i velike stope smrtnosti te nepostojanja učinkovitog cjepiva pristupilo se prenamjenjivanju lijekova razvijenih i korištenih za druga virusna oboljenja. Velik broj zaraženih sa sobom je povukao i veliku količinu korištenih farmaceutika koje postrojenja za obradu otpadnih voda nisu bila u mogućnosti ukloniti. Iz tog je razloga značajno porasla koncentracija farmaceutika detektiranih u površinskim vodama. Prisutnost ovih farmaceutika u okolišu predstavlja potencijalni rizik za ekosustave i ljudsko zdravlje. Ekotoksičnost ovih lijekova može imati negativan utjecaj na vodene organizme i ostale biološke vrste, čime se narušava ravnoteža ekosustava. Ovaj rad daje pregled najčešće korištenih farmaceutika za tretiranje bolesti COVID-19, njihove prisutnosti u okolišu, ekotoksikoloških ispitivanja provedenih sa svrhom ispitivanja utjecaja ovih lijekova na okoliš te načina njihovog mogućeg uklanjanja.

Abstract (english)

After the emergence of COVID-19 virus because of its infectibility and high death rate as well as non-existence of effective vaccine, repurposing of drugs made and used for other viral diseases was approached. A great number of infected caused a great amount of used pharmaceuticals that couldn’t be removed in wastewater treatment plants. For that reason there was a considerable rise in concentration of pharmaceuticals detected in surface waters. Presence of these pharmaceuticalse in the environment poses a potential risk for ecosystems and human health. Ecotoxicity of these pharmaceuticals can have a negative effect on water organisms and other biological species, which causes an imbalance in the ecosystem. This study provides an overview of the most commonly used pharmaceuticals for COVID-19 treatment, their presence in the environment, ecotoxicological experiments carried out with aim of observing the effect of said pharmaceuticals on the environment, as well as possible methods of their removal.

• Keywords: COVID-19; farmaceutici; ekotoksikološka ispitivanja; postupci uklanjanja
• Keywords (english): COVID-19; pharmaceuticals; ecotoxicology tests; methods of removal
• Language: croatian
• URN:NBN: urn:nbn:hr:149:944627
• Study programme: Title: Chemical Engineering - Undergraduate study; Study programme type: university; Study level: undergraduate; Academic / professional title: sveučilišni/a prvostupnik/prvostupnica (baccalaureus/baccalaurea) inženjer/inženjerka kemijskog inženjerstva (sveučilišni/a prvostupnik/prvostupnica (baccalaureus/baccalaurea) inženjer/inženjerka kemijskog inženjerstva)
• Type of resource: Text
• File origin: Born digital
• Access conditions: Open access; Embargo expiration date: 2024-01-01
• Created on: 2023-11-29 16:07:47