Razgradnja karbamazepina u vodi primjenom UV-C/H2O2 i UV-C/PAA procesa

master's thesis

• Title (english): Degradation of carbamazepine in water by UV-C/H2O2 and UV-C/PAA processes
• Author: Nina Kovač
• Mentor: Ana Lončarić Božić (mentor)
• Committee member: Ana Lončarić Božić (predsjednik povjerenstva)
• Committee member: Marin Kovačić (član povjerenstva)
• Committee member: Šime Ukić (član povjerenstva)
• Granter: University of Zagreb; Faculty of Chemical Engineering and Technology; Zagreb
• Defense date and country: 2019-09-27, Croatia
• Scientific / art field, discipline and subdiscipline: TECHNICAL SCIENCES; Chemical Engineering

Abstract

Farmaceutici širokog spektra primjene svakodnevno su u upotrebi kako u humanoj tako i u veterinarskoj medicini, a vrlo često zbog nemogućnosti njihovog uklanjanja konvencionalnim metodama obrade otpadnih voda bilo industrijskog ili komunalnog porijekla vrlo lako završavaju u pitkim vodama, ali i u sedimentu i u tlu. Zato se sve više radi na razvoju novih metoda za obradu otpadnih voda, a tu se najviše ističu napredni oksidacijski procesi. Posebno se ističu fotooksidacijski procesi u kojima se primjenom energije zračenja UV - C dijela spektra u kombinaciji s jakim oksidacijskim sredstvom iznimno brzo i učinkovito postiže razgradnja organskih onečišćujući tvari. U ovom radu ispitivana je mogućnost razgradnje modelne otpadne vode koja sadrži farmaceutik karbamazepin usporedbom dvaju fotooksidacijskih procesa, primjenom međusobno kompetitivnih oksidacijskih sredstava, vodikovog peroksida te peroctene kiseline. Primjenom metodologije odzivnih površina te dizajnom eksperimenta istražen je utjecaj procesnih parametara na učinkovitost obrade te su određeni optimalni uvjeti provedbe procesa. Ustanovljeno je da su optimalni uvjeti za proces fotooksidacije u kombinaciji s peroksidom pri pH 3 i [H2O2] = 9 mM procijenjeni kao podjednako značajni parametri procesa. S druge strane optimalni uvjeti za proces fotooksidacije u kombinaciji s peroctenom kiselinom iznosili su pH 3 i [PAA] = 5 mM, a pH otopine je procijenjen kao značajniji parametar procesa. Eksperimentalni rezultati u okviru zadanih raspona eksperimentalnih varijabli ukazuju na to da se brzina razgradnje karbamazepina procesom fotooksidacije u oba slučaja može opisati kinetičkim modelom prvog reda s pripadnim kinetičkim konstantama: 46,2·10^-3 s^-1 i 31,8·10^-3 s^-1 te mineralizacija modelom drugog reda s pripadnim kinetičkim konstantama: 5,3·10^-3 s^-1 i 4,7 ·10^-5 s^-1

Abstract (english)

Wide-ranging pharmaceuticals are used on daily basis in both human and veterinary medicine, but due to the inability to remove them by conventional wastewater treatment methods, either from industrial or municipal wastewater, very often they end up in drinking water, as well as in sediment and in soil. Therefore the necessity for the development of current wastewater treatment system is even more enhanced and advanced oxidation methods are considered as a new promising method. There should be noted that the photoxidation process which consider application of irradiation energy in UV-C spectra in combination with strong oxidizing agent results with highly efficient degradation of different organic pollutants. The aim of this study was to investigate the application of two photooxidation processes, with different oxidizing agents, hydrogen peroxide and peracetic acid for the degradation of the model wastewater that consist pharmaceutical carbamazepine as a pollutant. In this work, Design of experiments and Response surface methodology were used for the investigation of the process parameters on the efficiency of the process, as well as determination of the optimal process conditions. It is estimated that the pH value of solution and the concentration of oxidant have almost even level of importance and influence for the process, while the optimal pH =3 and [H2O2] = 9 mM. On the other hand, pH value of the solution has showed higher level of importance and influence for the process than the concentration of oxidant, while the optimal pH = 3 and [PAA] = 5 mM. Experimental results shows that the degradations of the carbamazepine by photooxidation in both cases can be described with first order kinetics with belonging constants: 46,2·10^-3 s^-1 and 31,8·10^-3 s^-1 and mineralization with second order kinetics with belonging constants: 5,3·10^-3 s^-1 and 4,7·10^-5 s^-1

• Keywords: napredni oksidacijski procesi; farmaceutici; karbamazepin; metoda odzivnih površina
• Keywords (english): advanced oxidation processes; pharmaceuticals; carbamazepine; response surface methodology
• Language: croatian
• URN:NBN: urn:nbn:hr:149:989223
• Project: Number: IP-2018-01-1982; Title: Nano-katalizatori aktivirani Sunčevim zračenjem u tehnologijama zaštite okoliša; Title: Nano-sized solar-active catalysts for environmental technologies; Acronym: NaSCEnT; Leader: Hrvoje Kušić; Jurisdiction: Croatia; Funder: HRZZ; Funding stream: IP
• Study programme: Title: Applied Chemistry - Graduate study; specializations in: Environmental chemistry and green technologies, Advanced materials and technologies, Applied organic chemistry; Course: Applied organic chemistry; Study programme type: university; Study level: graduate; Academic / professional title: magistar/magistra primijenjene kemije (magistar/magistra primijenjene kemije)
• Type of resource: Text
• File origin: Born digital
• Access conditions: Closed access
• Created on: 2022-02-22 11:36:02