Due to the continuos increase in the concentration of organic pollutants in water ecosystems, there is need to find technology for efficient tretment of industrial and municipal wastewater. Photocatalysis using titanium dioxide is already a well-established method of decomposition of organic pollutants, but the limited use of titanium dioxide only with activation by UV radiation presents a big challenge. During extensive research in this area, various methods of doping titanium dioxide with nonmetals or other photoactive metals were developed, as well as other TiO2 modification procedures aimed at reducing the band gap and reducing the rate of charged carrier recombination. However, in recent times, significant advances have been made in the field of zeolites and metal-organic frameworks as advanced materials with a large specific surface area and uniform structure, which opens up new possibilities for the preparation of composite photocatalysts and further improvement of the photocatalytic activity of existing photocatalysts whose constituent part is titanium dioxide. This paper describes the synthesis procedure of the hybrid TiO2/ZIF-8 photocatalyst and testing of its activity in a system for the photocatalytic degradation of the neonicotinoid insecticide imidacloprid under the conditions of UV irradiation achieved using a Pen Ray lamp. Hybrid photocatalysts were obained by hydrothermal synthesis at 150 ℃, using mechanochemically synthesized ZIF-8 and titanium tetraisopropoxide as precursor to titanium dioxide. Three photocatalysts with different amount of titanium dioxide (5, 50 and 95%) were synthesized and their adsorption and photocatalytic properties were investigated. The research was carried out in a suspension reactor with a volume of 80 mL, containing 80 mg of the catalyst sample at a rotation speed of 250 rpm. The initial concentration of imidacloprid was 10 ppm, and the pH was adjusted to 6,5. The degree of degradation of imidacloprid was determined by measuring the concentration of imidacloprid in time intervals of 15, 30 and 60 minutes using high performance chromatography. The characterization results showed successful synthesis of the hybrid photocatalyst with a reduction of the band gap from 5,0 eV to 3,1 – 3,6 eV compared to the starting sample (ZIF-8). The photocatalysts proved to be thermally stable up to 400 ℃ with a particle size below 1 μm. It was found that there is no change in the structure of the catalyst after its testing in the system. Despite the excellent adsorption capacity of ZIF-8 as the basic component of the hybrid photocatalysts, the hybrid photocatalysts showed poor adsorption properties. The efficiencyof the photodegradation of imidacloprid depends on the mass fraction of the photocatalytically active component, TiO2, deposited on the surface of ZIF-8. The hybrid photocatalyst containing 5% of TiO2 showed the highest efficiency.