Elektrokemijska oksidativna degradacija farmaceutika na različitim elektrodnim materijalima

undergraduate thesis

• Title (english): Electrochemical oxidative degradation of pharmaceuticals at different electrode materials
• Author: Margareta Postonjski
• Mentor: Marijana Kraljić Roković (mentor)
• Committee member: Marijana Kraljić Roković (predsjednik povjerenstva)
• Committee member: Iva Movre Šapić (član povjerenstva)
• Committee member: Elvira Vidović (član povjerenstva)
• Granter: University of Zagreb; Faculty of Chemical Engineering and Technology; Zagreb
• Defense date and country: 2021-09-21, Croatia
• Scientific / art field, discipline and subdiscipline: TECHNICAL SCIENCES; Chemical Engineering

Abstract

Cilj ovog rada bio je ispitati fotoelektrokemijska svojstva TiO2/SnS2 u vodenoj otopini 0,1 mol/dm^3 NaCl u prisustvu i bez prisustva farmaceutika ciprofloxacin (CIP) koncentracije 0,075 mmol/dm^3 te desvenlafaxine (DSV) i amoxicillin (AMOX) koncentracije 0,1 mmol/dm^3. Kao izvor svjetlosti korištena je LED svjetiljka. Provedena su i elektrokemijska ispitivanja u otopini farmaceutika na elektrodi od staklastog ugljika (GC elektroda). Metode elektrokemijske karakterizacije elektroda korištene u ovom radu su ciklička voltametrija, linearna polarizacija, elektrokemijska impendacijska spektroskopija i Mott-Schottsky analiza. Dobiveni rezultati ukazuju da se ispitani farmaceutici adsorbiraju na površinu TiO2/SnS2 elektrode što smanjuje brzinu reakcije pa su tako u prisustvu fartmaceutika dobivene manje vrijednosti fotostruja te je došlo do porasta otpor prijelazu naboja. Ispitivanja provođena na GC elektrodi pokazala su da ne dolazi do elektrokemijske oksidacije farmaceutika u ispitivanom području potencijala, s obzirom da nisu vidljivi karakteristični strujni vrhovi. Prilikom provođenja ispitivanja u inertnoj atmosferi i puferiranoj otopini uz rotaciju electrode dolazi do oksidacije farmaceutika pri čemu se formira strujni vrh.

Abstract (english)

The goal of this study was to examine the photoelectrochemical properties of TiO2/SnS2 electrode in 0.1 mol/dm^3 NaCl aqueous solution with the presence or absence of pharmaceuticals. The tests were performed in 0.075 mmol/dm^3 ciprofloxacin (CIP) solution and 0.1 mmol/dm^3 desvenlafaxine (DSV) and amoxicillin (AMOX) solutions with an LED lamp as a illumination source. Additional electrochemical measurements were done by using glassy carbon electrode (GC electrode). The methods of electrochemical characterization used in this work were cyclic voltammetry, linear polarization, electrochemical impedance spectroscopy, and the Mott-Schottky technique. The obtained results indicated that the tested pharmaceuticals were adsorbed on the surface of TiO2/SnS2 electrode, which resulted in lower values of photocurrents an increase in charge transfer resistance. Experiments performed on the GC electrode showed that there was no electrochemical oxidation of the pharmaceuticals in the tested potential range since no characteristic current peaks were visible. The measurements carried out in an inert atmosphere and a buffered solution with the rotating disc electrode, pointed out that oxidation of the pharmaceuticals was taking place.

• Keywords: amoxicillin; ciprofloxacin; desvenlafaxine; elektrokemijska fotokataliza; poluvodič
• Keywords (english): amoxicillin; ciprofloxacin; desvenlafaxine; electrochemical photocatalysis; semiconductor
• Language: croatian
• URN:NBN: urn:nbn:hr:149:952860
• Project: Number: IP-2018-01-1982; Title: Nano-katalizatori aktivirani Sunčevim zračenjem u tehnologijama zaštite okoliša; Title: Nano-sized solar-active catalysts for environmental technologies; Acronym: NaSCEnT; Leader: Hrvoje Kušić; Jurisdiction: Croatia; Funder: HRZZ; Funding stream: IP
• Project: Number: KK.01.1.1.04.0001; Title: Pročišćavanje vode i dobivanje energije korištenjem novih kompozitnih materijala uz Sunčevo zračenje; Leader: Hrvoje Kušić; Jurisdiction: eu; Funder: EC; Funding stream: KF
• Study programme: Title: Applied Chemistry - Undergraduate study; specializations in: Environmental chemistry and green technologies, Advanced materials and technologies, Applied organic chemistry; Course: Advanced materials and technologies; Study programme type: university; Study level: undergraduate; Academic / professional title: sveučilišni/a prvostupnik/prvostupnica (baccalaureus/baccalaurea) primijenjene kemije (sveučilišni/a prvostupnik/prvostupnica (baccalaureus/baccalaurea) primijenjene kemije)
• Type of resource: Text
• File origin: Born digital
• Access conditions: Open access
• Created on: 2023-04-14 07:45:42