Razvoj bežičnog optičkog kemijskog senzora za praćenje stanja rana

master's thesis

• Title (english): Development of a wireless optical chemical sensor for wound status monitoring
• Author: Marko Zubak
• Mentor: Ivana Steinberg (mentor)
• Committee member: Ivana Steinberg (predsjednik povjerenstva)
• Committee member: Petar Kassal (član povjerenstva)
• Committee member: Sanja Lučić Blagojević (član povjerenstva)
• Granter: University of Zagreb; Faculty of Chemical Engineering and Technology; Zagreb
• Defense date and country: 2017-07-12, Croatia
• Scientific / art field, discipline and subdiscipline: NATURAL SCIENCES; Chemistry; Applied Chemistry

Abstract

Bežični optički kemijski senzori omogućavaju olakšanu analizu bioloških uzoraka. Neinvazivnost postupka i kontinuirano praćenje u realnom vremenu samo su neke od prednosti nosivih kemijskih senzora u odnosu na klasične laboratorijske instrumente. Idealna primjena takvih senzora je bezbolno praćenje stanja rana. U tu svrhu razvijeno je pH osjetljivo bojilo 4-[4-(2-hidroksietansulfonil)-fenilazo]-2,6-dimetoksifenol, GJM-534, čija konstanta disocijacije odgovara području pH vrijednosti akutnih i kroničnih rana. U radu je provedena spektrofotometrijska karakterizacija imobiliziranog pH osjetljivog bojila na klasični zavoj i poliestersku foliju. Razvijen je pametni zavoj integriranjem imobiliziranog bojila i bežične platforme temeljene na radiofrekvencijskoj identifikaciji (RFID). Ovakva vrsta kemijskih senzora olakšava život oboljelima od kroničnih oblika bolesti koje zahtijevaju kontinuirano praćenje.

Abstract (english)

Wireless optical chemical sensors allow easier analysis of biological samples. Noninvasiveness of the procedure and continuous monitoring in real-time are only some of the advantages of wearable chemical sensors compared to conventional laboratory instruments. An ideal application of such sensors is painless monitoring of wounds. For that purpose it has been developed a pH sensitive dye 4-[4-(2-hydroxyethanesulfonyl)-phenylazo]-2,6-dimethoxyphenol, GJM-534, which has an acid dissociation constant in the range of pH values of acute and chronic wounds. In this work, the spectrophotometric characterization of the immobilized pH sensitive dye on the classic bandage and polyester foil was performed. A smart bandage has been developed by integrating the immobilized dye with a radio-frequency identification (RFID) based wireless platform. This type of sensor improve lives of people suffering from chronic forms of diseases which require continuous monitoring.

• Keywords: rane; bežične tehnologije; kemijski senzori; optički senzori; pH indikatori
• Keywords (english): wounds; wireless technology; chemical sensors; optical sensors; pH indicators
• Language: croatian
• URN:NBN: urn:nbn:hr:149:277733
• Study programme: Title: Chemical Engineering - Graduate study; Study programme type: university; Study level: graduate; Academic / professional title: magistar/magistra inženjer/inženjerka kemijskog inženjerstva (magistar/magistra inženjer/inženjerka kemijskog inženjerstva)
• Type of resource: Text
• File origin: Born digital
• Access conditions: Open access
• Created on: 2019-11-18 14:03:41